Leinco Technologies

Recombinant Mouse IL-5

Product Code:
 
LEI-I-532
Product Group:
 
Recombinant Proteins
Host Type:
 
Mouse
Regulatory Status:
 
RUO
Shipping:
 
Dry Ice
Storage:
 
Working aliquots of this recombinant protein solution are stable for up to twelve months at -20°C to -70°C in a manual defrost freezer. Upon thawing in the presence of a carrier protein this recombinant protein can be stored at 2° - 8°C for one month without detectable loss of activity. For long-term storage aliquot and freeze at -20°C to -70°C in a manual defrost freezer. Avoid repeated freeze thaw cycles.
 

No additional charges, what you see is what you pay! *

CodeSizePrice
LEI-I-532-5ug5 ug£574.00
Quantity:
LEI-I-532-25ug25 ug£1,495.00
Quantity:
Prices exclude any Taxes / VAT
How to order with us   Contact us
Stay in control of your spending. These prices have no additional charges, not even shipping!
* Rare exceptions are clearly labelled (only 0.14% of items!).
Multibuy discounts available! Contact us to find what you can save.
This product comes from: US.
Typical lead time: 14-21 working days.
Contact us for more accurate information.
  • Further Information
  • References
  • Related Products
  • Show All

Further Information

Format:
This recombinant protein solution was 0.2 um filtered and formulated in modified Dulbecco?s phosphate buffered saline (1X PBS) pH 7.2 ? 7.3 with no calcium, magnesium, or preservatives present.
Formulation:
This recombinant protein solution was 0.2 um filtered and formulated in modified Dulbecco?s phosphate buffered saline (1X PBS) pH 7.2 ? 7.3 with no calcium, magnesium, or preservatives present.
Long Description:
IL-5 is a 26 kD TH2 cytokine and a homodimeric glycoprotein that is part of the hematopoietic family. IL-5 stimulates B cell growth as well as increases Ig secretion. It is the main factor that promotes the terminal differentiation of eosinophil progenitors and enhances the effector capacity of mature eosinophils. IL-5 is a major regulator of eosinophil accumulation in tissues. In fact, in Hodgkin lymphoma, the characteristically observed eosinophilia is suspected to result from an increased production of IL-5. IL-5 may also be the cause of several allergic diseases including asthma, where it is thought that eosinophils have a significant role in the disease pathology. There are several mAbs currently in use that target IL-5 for the treatment of severe eosinophilic asthma.
NCBI Gene:
16191
Purity:
>97% by SDS-PAGE and analyzed by silver stain.
Target:
IL-5

References

1. Capron, M. et al. (1994) J Exp Med 179: 703 2. Graber, P. et al. (1993) Nature 363: 172 3. Inokuma, S. et al. (2005) Int Arch Allergy Immunol 1: 55