Leinco Technologies

Anti-Rat ALK-7 (Clone 118310)

Product Code:
 
LEI-A379
Product Group:
 
Primary Antibodies
Host Type:
 
Mouse
Antibody Isotype:
 
IgG2a
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
118310
Regulatory Status:
 
RUO
Target Species:
 
Rat
Application:
 
Western Blot (WB)
Shipping:
 
Ambient
Storage:
 
The lyophilized antibody can be stored desiccated at -20°C to -70°C for up to twelve months. The reconstituted antibody can be stored for at least four weeks at 2-8°C. For long-term storage of the reconstituted antibody aseptically aliquot into working volumes and store at -20°C to -70°C in a manual defrost freezer. Avoid repeated freeze thaw cycles. No detectable loss of activity was observed after six months.
 

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CodeSizePrice
LEI-A379-25ug25 ug£375.00
Quantity:
LEI-A379-500ug500 ug£773.00
Quantity:
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This product comes from: US.
Typical lead time: 14-21 working days.
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Further Information

Conjugate/Tag/Label:
Purified No Carrier Protein
Format:
This monoclonal antibody has been 0.2 um filtered and lyophilized from modified Dulbecco's phosphate buffered saline (1X PBS) pH 7.2 - 7.3 containing 5.0% w/v trehalose with no calcium, magnesium or preservatives present.
Formulation:
This monoclonal antibody has been 0.2 um filtered and lyophilized from modified Dulbecco's phosphate buffered saline (1X PBS) pH 7.2 - 7.3 containing 5.0% w/v trehalose with no calcium, magnesium or preservatives present.
Immunogen:
NS0-Derived Recombinant Rat ALK-7 Extracellular Domain
Long Description:
Activin receptor-like kinase (ALK) 7 is a type I serine/threonine kinase receptor of the transforming growth factor (TGF)-beta family of proteins.1 ALK7 is most abundantly expressed in human brain, pancreas and colon.2 It negatively regulates glucose-stimulated insulin release in β-cells3 and plays an important role in regulating the functional plasticity of pancreatic islets.3 ALK7 also has an important role in the regulation of body fat deposition. These has implications for the development of treatments against diabetes and obesity.3
NCBI Gene:
245921
Target:
ALK-7

References

1. Kim, SJ. et al. (2004) J Biol Chem. 279: 28458 2. Ritvos, O. et al. (2001) Cytogenet Cell Genet. 95: 157 3. Ibanez, CF. et al. (2008) Proc Natl Acad Sci USA 105: 7246