Leinco Technologies

Recombinant Mouse PDGF-AA

Product Code:
 
LEI-P297
Product Group:
 
Recombinant Proteins
Host Type:
 
Mouse
Regulatory Status:
 
RUO
Shipping:
 
Ambient
Storage:
 
The lyophilized protein should be stored desiccated at -20°C. The reconstituted protein can be stored for at least one week at 4°C. For long-term storage of the reconstituted protein aliquot into working volumes and store at -20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
 

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CodeSizePrice
LEI-P297-10ug10 ug£307.00
Quantity:
LEI-P297-100ug100 ug£694.00
Quantity:
LEI-P297-500ug500 ug£3,072.00
Quantity:
LEI-P297-1mg1 mg£5,063.00
Quantity:
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This product comes from: US.
Typical lead time: 14-21 working days.
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  • Further Information
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Further Information

Long Description:
Platelet-derived growth factor (PDGF), an agent with important mitogenic effects for bone cells, exists in three isoforms, PDGF-AA, - BB, and ?AB.1 The A-chain homodimers of the platelet-derived growth factor (PDGF AA) are widely expressed in normal and transformed cells.2 PDGF AA is a potent mitogen for a wide range of cell types including fibroblast, smooth muscle, and connective tissue. PDGF-AA and its receptor represent an important epithelial-mesenchymal interaction which plays a critical role in early lung branching morphogenesis.3 PDGF AA is also an essential autocrine regulator for vascular endothelial growth factor (VEGF) expression. It regulates the frequency and level of VEGF expression during the transition from a precancerous lesion to advanced cancer.4
NCBI Gene:
18590
Purity:
>97% by SDS Page and HPLC
Target:
PDGF-AA

References

1. Canalis, E. et al. (1994) Endocrin. 134: 25412. Deuel, TF. et al. (1992) Biochem Biophys Res Commun. 186: 15103. Post, M. et al. (1995) Endocrin. 121: 255294. Sueishi, K. et al. (2005) Cancer Research 65: 7241