Leinco Technologies

Recombinant Human FGF-Basic (146 aa)

Product Code:
 
LEI-F1105
Product Group:
 
Recombinant Proteins
Host Type:
 
Human
Regulatory Status:
 
RUO
Shipping:
 
Ambient
Storage:
 
This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.
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CodeSizePrice
LEI-F1105-25ug25 ug£273.00
Quantity:
LEI-F1105-500ug500 ug£386.00
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LEI-F1105-10ug10 ug£3,060.00
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This product comes from: US.
Typical lead time: 14-21 working days.
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Further Information

Format:
This recombinant protein was 0.2 um filtered and lyophilized from a sterile solution containing 20 mM Tris, 1000 mM NaCl pH 7.0.
Formulation:
This recombinant protein was 0.2 um filtered and lyophilized from a sterile solution containing 20 mM Tris, 1000 mM NaCl pH 7.0.
Long Description:
Basic fibroblast growth factor (bFGF), also known as FGF-2 and FGF-β, is a non-glycosylated heparin binding growth factor and member of the FGF family of mitogenic proteins. Members of this family play a central role during prenatal development, postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation (1). bFGF is expressed in the brain, pituitary, kidney, retina, bone, testis, adrenal gland, liver, placenta, and monocytes, epithelial and endothelial cells. It is secreted by mechanisms other than the classical protein secretion pathway due to the lack of a signal peptide. Acidic FGF (aFGF) and bFGF bind to the same high affinity receptors (2). Binding of bFGF to heparin or cell surface heparan sulfate proteoglycans is a prerequisite for ligation of bFGF to these receptors. aFGF and BFGF have a similar range of biological activities which are implicated in several important physiological and pathological processes, such as embryonic development and differentiation, morphogenesis, angiogenesis, and wound healing (3-4).
NCBI Gene:
2247
Purity:
>97% by SDS-PAGE and analyzed by silver stain.
Target:
FGF-Basic

References

1. Swain, JL. et al. (1991) Developement 111: 741 2. Grevers, G. et al. (1997) Laryngorhinootologie 76: 421 3. B?hring, HJ. et al. (2007) Differentiation. 75(4):279-91