Leinco Technologies

Recombinant Mouse Eotaxin-2 (aa 27-119)

Product Code:
 
LEI-E307
Product Group:
 
Recombinant Proteins
Host Type:
 
Mouse
Regulatory Status:
 
RUO
Shipping:
 
Ambient
Storage:
 
This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.
 

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LEI-E307-25ug25 ug£443.00
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This product comes from: US.
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Further Information

Format:
This recombinant protein Mouse Eotaxin-2 was 0.2 um filtered and lyophilized from a PBS Solution.
Formulation:
This recombinant protein Mouse Eotaxin-2 was 0.2 um filtered and lyophilized from a PBS Solution.
Long Description:
Eotaxin-2, also known as MPIF-2 and CCL24, is a member of the CC chemokine family. It interacts with chemokine receptor CCR3 to induce chemotaxis in eosinophils and the release of histamine and leukotriene C4 from basophils primed with IL-3 (1). This chemokine is also strongly chemotactic for resting T lymphocytes and slightly chemotatic for neutrophils (2). Murine Eotaxin-2 appears to be produced constitutively in the jejunum and spleen. Production is induced by allergen challenge and IL-4 overexpression (3). LPS and IL-4 also differentially regulate the expression of Eotaxin-2 in monocytes and macrophages. Additionally, Eotaxin-2 inhibits the proliferation of multipotential hematopoietic progenitor cells (4). Functionally, Eotaxin-2 is most closely related to Eotaxin/CCL11 and Eotaxin-3/CCL26.
NCBI Gene:
56221
Purity:
>97% by SDS-PAGE and analyzed by silver stain.
Target:
Eotaxin-2

References

1. Forssmann, U. et al. (1997) J. Exp. Med. 185:2171 2. Patel, VP. et al. (1997) J. Exp. Med. 185:1163 3. Zimmerman, N. et al. (2000) J. Immunol. 1168:1911 4. Pope, S. M. et al. (2005) J. Immunol. 175:5341