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Leinco Technologies

Anti-Mouse CD3 (17A2) - Purified in vivo GOLD™ Functional Grade

Product Code:
 
LEI-C2443
Product Group:
 
Primary Antibodies
Host Type:
 
Rat
Antibody Isotype:
 
IgG2b κ
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
17A2
Regulatory Status:
 
RUO
Target Species:
 
Mouse
Applications:
  • Co-stimulation
  • Flow Cytometry
  • Immunohistochemistry- Frozen Section (IHC-F)
  • In Vivo Assay
  • Spatial Biology
Shipping:
 
2-8°C
Storage:
 
Functional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one month. For longer term storage aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles.
 

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CodeSizePrice
LEI-C2443-0.5mg0.5 mg£243.00
Quantity:
LEI-C2443-1.0mg1.0 mg£404.00
Quantity:
LEI-C2443-5.0mg5.0 mg£974.00
Quantity:
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This product comes from: US.
Typical lead time: 14-21 working days.
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Further Information

Antigen Distribution:
CD3 is expressed on human peripheral blood lymphocytes, splenic lymphocytes, and the majority of T-CLL and T-ALL cells.
Concentration:
?1.0 mg/ml
Conjugate/Tag/Label:
in vivo GOLD™, Purified in vivo Functional Grade
Format:
This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added. Due to inherent biochemical properties of antibodies, certain products may be prone to precipitation over time. Precipitation may be removed by aseptic centrifugation and/or filtration.
Formulation:
This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added. Due to inherent biochemical properties of antibodies, certain products may be prone to precipitation over time. Precipitation may be removed by aseptic centrifugation and/or filtration.
Immunogen:
γ/δ TCR-positive T-T hybridoma D1
Long Description:
CD3ε is a 20kDa subunit of the TCR complex and is a transmembrane T-cell surface glycoprotein that belongs to the Ig superfamily. It is one of five polypeptide chains that form the TCR complex by associating with the CD3δ, γ and ζ chains, in addition to the TCR α/β or γ/δ chains. CD3 is involved in TCR signaling, enumeration of immunocompetent T-lymphocytes in peripheral blood, and signal transduction during antigen recognition.
NCBI Gene:
12502
Purity:
?95% monomer by analytical SEC, >95% by SDS Page
Target:
CD3

References

1. Gallimore, A. et al. (2005) J Immunol. 175(11):7098-102. PubMed 2. Mysliwietz, J. et al. (1992) Blood 80: 2661-2667