MBL

Anti-GST-pi (Human) pAb

Product Code:
 
MBL-312
Product Group:
 
Primary Antibodies
Supplier:
 
MBL
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Shipping:
 
4°C
Storage:
 
-20°C
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MBL-312100 ul£296.00
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  • Further Information
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Further Information

Alternative Names:
GSTP1 glutathione S-transferase pi 1, PI DFN7 GST3 GSTP FAEES3
Applications:
WB - 1:500-1:1000 (chemiluminescence detection system) IHC - 1:500-1:1000 (frozen sections, paraffin sections)
Background:
GST-Π is a 26kDa protein that belongs to the GST superfamily of enzymes which have an important role in detoxification. They catalyze the conjugation of many hydrophobic and electrophophilic compounds with reduced glutathione. There are four main classes: α, u, Π and ?. Results indicate that GST- Π is the most accurate marker enzyme for detection of initiated cells during liver carcinogenesis, preneoplasia, colonic carcinoma and lung carcinoma.
Formulation:
In PBS/50% glycerol, pH 7.2
Gene IDs:
Human: 2950
Immunogen Translated:
Purified human glutatione S-transferase pi
Reactivity:
This antibody reacts with GST- Π, and doesn?t react with other isozymes on Western blotting.
Shelf Life:
1 year
Source:
This antibody was purified from rabbit serum using protein A agarose. The rabbit was immunized with purified human glutathione S-transferase Π.
Target:
GST-pi

Documents

References

1) Boku, N., et al., Jpn. J. Clin. Oncol. 37, 275-281 (2007) 2) Gu, M., et al., Cancer Res. 67, 3483-3491 (2007) 3) Nagashima, F., et al., Jpn. J. Clin. Oncol. 35, 714-719 (2005) 4) Tsuchida, S., et al., Cancer Res. 49, 5225-5229 (1989) 5) Sato, K., et al., Adv. Cancer Res. 52, 205-255 (1989) 6) Eimoto, H., et al., Carcinogenesis 9, 2325-2327 (1988) 7) Shiratori, Y., et al., Cancer Res. 47, 6806-6809 (1987) 8) Batist, G., et al., J. Biol. Chem. 261, 15544-15549 (1986) 9) Soma, Y., et al., Biochim. Biophys. Acta. 869, 247-258 (1986) This antibody is used in the reference number 1)-3).