MBL

Anti-CD32 (Human) mAb Functional Grade

Product Code:
 
MBL-FP10202550
Product Group:
 
Primary Antibodies
Supplier:
 
MBL
Host Type:
 
Mouse
Antibody Isotype:
 
IgG1 κ
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
6C4
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Flow Cytometry
  • Functional Study
Shipping:
 
4°C
Storage:
 
4°C
 

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MBL-FP10202550500 ug£699.00
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This product comes from: United States.
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Further Information

Background:
The 6C4 monoclonal antibody specifically recognizes two isoforms of human CD32, Fc gamma RIIA and Fc gamma RIIB. From alternative mRNA splicing, 6 isoforms of CD32 have been reported. CD32 is a 40 kDA polymorphic transmembrane glycoprotein expressed on monocytes, macrophages, graulocytes, B cells, and platelets. The receptor has low affinity toward IgG and is involved in immunomodulation, phagocytosis, and the inflammation response. The 6C4 antibody in a rosette blocking assay is reported to inhibit Ig binding
Concentration:
1 mg/mL
Formulation:
Phosphate-buffered aqueous solution, ph7.2.
Target:
CD32

Documents

References

Tedder, T. F., et al., J Immunol. 133, 678-683 (1984) Fingeroth, J. D., et al., Proc Natl Acad Sci U S A. 81, 4510-4514 (1984) Nemerow, G. R., et al., J Virol. 55, 347-351 (1985)