MBL

Anti-PD-1 (CD279) (Human) mAb-FITC

Product Code:
 
MBL-FP10915002
Product Group:
 
Primary Antibodies
Supplier:
 
MBL
Host Type:
 
Mouse
Antibody Isotype:
 
IgG1 κ
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
MIH4
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Flow Cytometry
Shipping:
 
4°C
Storage:
 
4°C
 

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MBL-FP1091500225 tests£277.00
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Further Information

Background:
The MIH4 monoclonal antibody specifically reacts with human Programmed death-1 (PD-1 or CD279), a 50-55 kDA glycoprotein. It is expressed on mainly on activated B, T, and myeloid cells. Within the cytoplasmic region, PD-1 contains an Immunoreceptor tyrosine-based inhibitory motif (ITIM) and seems to regulate peripheral tolerance. The lack or mutation of CD279 is linked to autoimmune disorders.
Concentration:
5 uL (2 ug)/test
Conjugate:
FITC
Formulation:
Phosphate-buffered aqueous solution, ?0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Target:
PD-1

Documents

References

Schlossman, S. F., Leukocyte typing V. Oxford University Press (1995) Zhang, B., et al., Ann Rheum Dis. 67, 1037-1040 (2008) Chapel, A., et al., J Virol. 66, 3966-3970 (1992)