MBL

Anti-CD40 (Mouse/Rat) mAb Functional Grade

Product Code:
 
MBL-FP2003251K
Product Group:
 
Primary Antibodies
Supplier:
 
MBL
Host Type:
 
Hamster
Antibody Isotype:
 
IgM κ
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
HM40-3
Regulatory Status:
 
RUO
Target Species:
 
Mouse
Applications:
  • Flow Cytometry
  • Functional Study
Shipping:
 
4°C
Storage:
 
4°C
 

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MBL-FP2003251K1 mg£1,023.00
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This product comes from: United States.
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  • Further Information
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Further Information

Background:
The HM40-3 monoclonal antibody reacts with mouse CD40, a 48kDA type I glycoprotein known as Bp50. CD40 is part of the TNFR family and expressed on a subset of T cells, B cells, dendritic cells, and macrophages. It has been shown to be involved in the protection of B cells from apoptosis, B cell differentiation, co-stimulation, and isotype class-switching. The HM40-3 antibody blocks the binding of CD40L (CD154) and stimulates B and dendritic cell proliferation.
Concentration:
1 mg/mL
Formulation:
Phosphate-buffered aqueous solution, ph7.2.
Target:
CD40

Documents

References

Sanchez-Madrid, F., et al., J Exp Med. 158, 586-602 (1983) Ault, K. A., & Springer, T. A., J Immunol. 126, 359-364 (1981) Springer, T., et al., Eur J Immunol. 8, 539-551 (1978)