MBL

Anti-CD40 Ligand (CD154) (Mouse) mAb-PE

Product Code:
 
MBL-FP20486010
Product Group:
 
Primary Antibodies
Supplier:
 
MBL
Host Type:
 
Hamster
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
MR1
Regulatory Status:
 
RUO
Target Species:
 
Mouse
Application:
 
Flow Cytometry
Shipping:
 
4°C
Storage:
 
4°C
 

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MBL-FP20486010100 ug£374.00
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Further Information

Background:
The MR1 monoclonal antibody specifically reacts with mouse CD154, a 39kDA transmembrane glycoprotein also known as CD40 ligand and gp39. CD154 is expressed on activated T cells and plays a role in B-T cell costimulation. The interaction of CD154 with CD40 induces B cell cycle entry and the signaling for T-dependent B cell activation. By interfering with this interaction, the MR1 antibody is reported to inhibit T and B lymphocyte activation.
Concentration:
0.2 mg/mL
Conjugate:
PE
Formulation:
Phosphate-buffered aqueous solution, ?0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Target:
CD40 Ligand

Documents

References

Barclay, A., et al., The leucocyte antigen factsbook. Academic Press, London (1997) Pulendran, B., et al., J Immunol. 159, 2222-2231 (1997) Xin, K. Q., et al., J Virol. 80, 11899-11910 (2006)