Elabscience

PerCP/Cyanine5.5 Anti-Mouse CD127/IL-7RA Antibody[A7R34]

Product Code:
 
E-AB-F1023J
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rat
Antibody Isotype:
 
Rat IgG2a, κ
Antibody Clone:
 
A7R34
Regulatory Status:
 
RUO
Target Species:
 
Mouse
Application:
 
Flow Cytometry
Shipping:
 
Ice packs
Storage:
 
Store at 2-8°C and protected from prolonged exposure to light. Do not freeze.
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C57BL/6 murine splenocytes are stained with PerCP/Cyanine5.5 Anti-Mouse CD127/IL-7RA Antibody and Elab Fluor® 488 Anti-Mouse CD3 Antibody (Left). Splenocytes stained with Elab Fluor® 488 Anti-Mouse CD3 Antibody (Right) are used as control.
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C57BL/6 murine splenocytes are stained with PerCP/Cyanine5.5 Anti-Mouse CD127/IL-7RA Antibody and Elab Fluor® 488 Anti-Mouse CD3 Antibody (Left). Splenocytes stained with Elab Fluor® 488 Anti-Mouse CD3 Antibody (Right) are used as control.

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CodeSizePrice
E-AB-F1023J-50Tests50Tests£142.00
Quantity:
E-AB-F1023J-100Tests100Tests£184.00
Quantity:
E-AB-F1023J-100Testsx2100Testsx2£261.00
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Further Information

Abbreviation:
CD127
Background:
CD127 is a 60-90 kD type I transmembrane glycoprotein also known as IL-7 receptor α chain or IL-7Rα. It forms a heterodimer with the common γ chain (γc or CD132) which is shared with the receptors for IL-2, IL-4, IL-9, IL-13, IL-15, and IL-21. CD127 is expressed on immature B cells through early pre-B stage, thymocytes (except CD4/CD8 double positive thymocytes), peripheral T cells, and bone marrow stromal cells. CD127 has been reported to be an useful marker for identifying memory and effector T cells. The ligation of IL-7 with its receptor is important for stimulation of mature and immature T cells as well as immature B cells proliferation and development.
Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Concentration:
5 uL/Test
Conjugation:
PerCP/Cyanine5.5
GeneID:
16197
Target Synonym:
Interleukin-7 receptor subunit alpha;Il7r;IL-7 receptor subunit alpha;IL-7R subunit alpha;IL-7R-alpha;IL-7RA;CD127;
UNIProt ID:
P16872
Usage:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 uL of antibody per test (million cells in 100 uL staining volume or per 100 uL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

Documents

References

  • https://www.hindawi.com/journals/omcl/2023/2894695/