Elabscience

Recombinant Human/Cynomolyus CD28/TP44 (C-Fc-Avi) Biotinylated

Product Code:
 
PKSH033948
Product Group:
 
Recombinant Proteins
Supplier:
 
Elabscience
Host Type:
 
Mixed
Regulatory Status:
 
RUO
Application:
 
Enzyme-Linked Immunosorbent Assay (ELISA)
Shipping:
 
This product is provided as lyophilized powder which is shipped with ice packs.
Storage:
 
Generally lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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Immobilized Anti-CD28 mAb at 2ug/ml (100 ul/well) can bind Human/Cynomolgus CD28-Fc-Avi. The ED50 of Human/Cynomolgus CD28-Fc-Avi is 0.84 ng/ml.

Immobilized Anti-CD28 mAb at 2ug/ml (100 ul/well) can bind Human/Cynomolgus CD28-Fc-Avi. The ED50 of Human/Cynomolgus CD28-Fc-Avi is 0.84 ng/ml.

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CodeSizePrice
PKSH033948-20ug20ug£368.00
Quantity:
PKSH033948-100ug100ug£757.00
Quantity:
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This product comes from: China.
Typical lead time: 14-21 working days.
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Further Information

Abbreviation:
CD28;TP44
Accession:
P10747
Activity:
Immobilized Anti-CD28 mAb at 2ug/ml (100 ul/well) can bind Human/Cynomolgus CD28-Fc-Avi. The ED50 of Human/Cynomolgus CD28-Fc-Avi is 0.84 ng/ml.
Background:
T-cell-specific surface glycoprotein CD28(CD28) is a single-pass typeI membrane protein which contains one Ig-likeV-type (immunoglobulin-like) domain. It belongs to the immunoglobulin(Ig) superfamily. CD28 is one of the molecules expressed on T cells that provide co-stimulatory signals, which are required for T cell activation.CD28 co-stimulation is necessary for CD4 positive T-cell proliferation and survival, interleukin-2 production, and T-helper type-2 development. Human post-thymic regulatory T cells require CD28 co-stimulation to expand and maintain potent suppressive function in vivo. Apoptosis plays a key role in the age-related decline of CD28 expression and in immunosenescence. CD28 is the receptor for CD80 (B7.1) and CD86 (B7.2). When activated by Toll-like receptor ligands, the CD80 expression is upregulated in antigen presenting cells (APCs). The CD86 expression on antigen presenting cells is constitutive. CD28 is the only B7 receptor constitutively expressed on naive T cells.
Calculated MW:
44.1 kDa
Conjugation:
Biotinylated
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
HEK293 Cells
Formulation:
Lyophilized from a 0.2 um filtered solution of 20mTris-HCl, 150mM NaCl, pH 8.0.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
C-Fc-Avi
ObservedMW:
60-90 kDa
Purity:
> 95 % as determined by reducing SDS-PAGE.
Sequence:
Asn19-Pro152
Target Synonym:
CD28;CD28 antigen;CD28 molecule;T-cell-specific surface glycoprotein CD28;Tp44;TP44
UNIProt ID:
P10747

Documents