Elabscience

Recombinant Cynomolgus FGL1 (C-6His)

Product Code:
 
PKSQ050095
Product Group:
 
Recombinant Proteins
Supplier:
 
Elabscience
Host Type:
 
Monkey
Regulatory Status:
 
RUO
Application:
 
Bio-Layer Interferometry
Shipping:
 
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt store it immediately at < -20°C.
Storage:
 
Store at < -20°C stable for 6 months after receipt. Please minimize freeze-thaw cycles.
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Loaded Cynomolgus LAG-3-Fc(Cat#PKSQ050015) on Protein A Biosensor, can bind Cynomolgus FGL1-His(Cat#PKSQ050095) with an affinity constant of 28.6nM as determined in BLI assay.
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Loaded Cynomolgus LAG-3-Fc(Cat#PKSQ050015) on Protein A Biosensor, can bind Cynomolgus FGL1-His(Cat#PKSQ050095) with an affinity constant of 28.6nM as determined in BLI assay.

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CodeSizePrice
PKSQ050095-10ug10ug£197.00
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PKSQ050095-50ug50ug£434.00
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Further Information

Abbreviation:
FGL1
Accession:
A0A2K5X990
Activity:
Loaded Cynomolgus LAG-3-Fc(Cat#PKSQ050015) on Protein A Biosensor, can bind Cynomolgus FGL1-His(Cat#PKSQ050095) with an affinity constant of 28.6nM as determined in BLI assay.
Background:
Hepassocin, also known as hepatocyte-derived fibrinogen-related protein 1 (HFREP-1), is a liver-specific secreted protein belonging to the fibronogen superfamily, whose members share a fibrinogen domain at their C-termini. It is secreted by the liver and functions as a mitogen for hepatocytes. Hepassocin may play a role in the development of hepatocellular carcinomas. Hepassocin is a disulfide-linked homodimeric protein with a C-terminal fibrinogen domain. It is reported that it is a major immune inhibitory ligand of LAG-3 .
Calculated MW:
34.8 kDa
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
HEK293 Cells
Formulation:
Supplied as a 0.2 um filtered solution of 20mM Tris-HCl, 10% Trehalose, 300mM NaCl, 50% Glycerol, 0.05% Tween 80, pH 8.5
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
C-6His
ObservedMW:
35 kDa
Purity:
> 95 % as determined by reducing SDS-PAGE.
Sequence:
Leu23-Ile312
Target Synonym:
Angiopoietin-related protein 4;425O18-1;Angiopoietin-like protein 4;Fasting-induced adipose factor;Hepatic fibrinogen/angiopoietin-related protein;HFARP;Secreted protein Bk89;Angptl4;Farp;Fiaf;Ng27
UNIProt ID:
A0A2K5X990

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