Elabscience

Recombinant Mouse Pentraxin-related protein PTX3(N-6His)

Product Code:
 
PKSM041439
Product Group:
 
Recombinant Proteins
Supplier:
 
Elabscience
Host Type:
 
Mouse
Regulatory Status:
 
RUO
Shipping:
 
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt store it immediately at < -20°C.
Storage:
 
Store at < -20°C stable for 6 months after receipt. Please minimize freeze-thaw cycles.
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PKSM041439-10ug10ug£255.00
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PKSM041439-50ug50ug£600.00
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Further Information

Abbreviation:
Pentraxin-relatedPTX3
Accession:
P48759
Background:
Pentraxin-related protein PTX3, also known as Tumor necrosis factor-inducible gene 14 protein (TSG-14), belongs to the pentraxin family. PTX3 plays a role in the regulation of innate resistance to pathogens, inflammatory reactions, possibly clearance of self-components and female fertility. It?s subunit is a disulfide-linked homooctamer that binds to C1q. PTX3 concentration is elevated in the joint fluid of patients with rheumatoid arthritis (RA), indicating that PTX3 may be a potential mediator of immune response. PTX3 may also function in the regulation of the uptake and clearance of apoptotic cells by dendritic cells. An in vivo study showed that PTX3 transgenic mice are more resistant to sepsis and endotoxemia compared to wild-type during inflammatory injury.
Calculated MW:
41 kDa
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
HEK293 Cells
Formulation:
Supplied as a 0.2 um filtered solution of PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
N-6His
ObservedMW:
54 kDa
Purity:
> 90 % as determined by reducing SDS-PAGE.
Sequence:
His18-Ser381
Target Synonym:
alpha-induced protein 5;pentaxin-related gene;rapidly induced by IL-1 beta;tumor necrosis factor;Pentaxin-related protein PTX3;Pentraxin 3;pentraxin 3;long;pentraxin-3;pentraxin-related gene;rapidly induced by IL-1 beta;pentraxin-related protein PTX3;PTX3;TNF alpha-induced protein 5;TNFAIP5;TSG14;TSG-14
UNIProt ID:
P48759

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