Elabscience

Recombinant Mouse TrkC/Ntrk3 (C-6His)

Product Code:
 
PKSM041444
Product Group:
 
Recombinant Proteins
Supplier:
 
Elabscience
Host Type:
 
Mouse
Regulatory Status:
 
RUO
Shipping:
 
This product is provided as lyophilized powder which is shipped with ice packs.
Storage:
 
Generally lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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CodeSizePrice
PKSM041444-10ug10ug£207.00
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PKSM041444-50ug50ug£466.00
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This product comes from: China.
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Further Information

Abbreviation:
TrkC;Ntrk3
Accession:
Q6VNS1
Background:
Three Trk family proteins, TrkA, TrkB, and TrkC, exhibiting different ligand specificities, have been identified. TrkA binds NGF and NT-3, TrkB binds BDNF, NT-3 and NT-4/5, and TrkC only binds NT-3. The primary location of TrkC expression is in the nervous system and, specifically, in regions of the CNS. Low level TrkC expression has also been observed in a wide variety of tissues outside the nervous system. Receptor tyrosine kinase involved in nervous system and probably heart development. Upon binding of its ligand NTF3/neurotrophin-3, NTRK3 autophosphorylates and activates different signaling pathways, including the phosphatidylinositol 3-kinase/AKT and the MAPK pathways, that control cell survival and differentiation.
Calculated MW:
45.5 kDa
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
HEK293 Cells
Formulation:
Lyophilized from a 0.2 um filtered solution of PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
C-6His
ObservedMW:
80-110 kDa
Purity:
> 95 % as determined by reducing SDS-PAGE.
Sequence:
Cys32-Thr429
Target Synonym:
GP145-TrkC;TrkC;trk-C;Neurotrophic tyrosine kinase receptor type 3;TrkC tyrosine kinase;NT-3 Growth Factor Receptor
UNIProt ID:
Q6VNS1

Documents