Elabscience

Recombinant Human Glypican-3/GPC3/OCI5 (C-6His-Avi) Biotinylated

Product Code:
 
PKSH033852
Product Group:
 
Recombinant Proteins
Supplier:
 
Elabscience
Host Type:
 
Human
Regulatory Status:
 
RUO
Application:
 
Enzyme-Linked Immunosorbent Assay (ELISA)
Shipping:
 
This product is provided as lyophilized powder which is shipped with ice packs.
Storage:
 
Generally lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
 

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CodeSizePrice
PKSH033852-20ug20ug£351.00
Quantity:
PKSH033852-100ug100ug£819.00
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This product comes from: China.
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Further Information

Abbreviation:
Glypican-3;GPC3;OCI5
Accession:
P51654
Activity:
Immobilized Human FGFb (Cat#C779) at 10ug/ml (100 ul/well) can bind Human Glypican-3-His(Cat#CY15). The ED50 of Human NRG1Beta-His (Cat#CH84) is 4. 5 ug/ml.
Background:
Glypican-3/GPC3 is a member of the glypican family. It belongs to the glypican family and is highly expressed in lung, liver, and kidney. It is a heparan sulfate proteoglycan, which is overexpressed in various neoplasms such as hepatocellular carcinoma, malignant melanoma, and testicular yolk sac tumor, and plays an important role in cell growth and differentiation. GPC3 function is tissue dependent. In some tissues, GPC3 acts as a tumor suppressor gene, whereas in others, it acts as an oncofetal protein. GPC3 is a reliable marker for hepatocellular carcinoma. The sensitivity and specificity exceeds both alpha-fetoprotein and hepatocyte-paraffin1. GPC3 immunohistochemistry can aid in the differentiation of testicular germ cell tumors, being expressed in all yolk sac tumors but not in seminomas. GPC3 expression has also been identified in some squamous cell carcinomas of the lung and clear cell carcinomas of the ovary. Glypican-3 is currently regarded as a tumor marker and potential target for immunotherapy.
Calculated MW:
63.4 kDa
Conjugation:
Biotinylated
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
HEK293 Cells
Formulation:
Lyophilized from a 0.2 um filtered solution of PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
C-6His-Avi
ObservedMW:
70-130&40 kDa
Purity:
> 95 % as determined by reducing SDS-PAGE.
Sequence:
Gln25-His559
Target Synonym:
Sialic acid-binding Ig-like lectin 9;Siglec-9;CDw329;Protein FOAP-9;SIGLEC9
UNIProt ID:
P51654

Documents