Elabscience

Recombinant Human Dickkopf-Related Protein 1/DKK-1 (C-Avi-6His) Biotinylated

Product Code:
 
PKSH034043
Product Group:
 
Recombinant Proteins
Supplier:
 
Elabscience
Host Type:
 
Human
Regulatory Status:
 
RUO
Shipping:
 
This product is provided as lyophilized powder which is shipped with ice packs.
Storage:
 
Generally lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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PKSH034043-20ug20ug£351.00
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PKSH034043-100ug100ug£819.00
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This product comes from: China.
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Further Information

Abbreviation:
DKK1;Dkk-1
Accession:
O94907
Background:
Dickkopf-related protein 1(DKK-1), is a member of the dickkopf family. DKK1 secreted proteins with two cysteine-rich domains separated by a linker region. It antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease.
Calculated MW:
28.4 kDa
Conjugation:
Biotinylated
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
HEK293 Cells
Formulation:
Lyophilized from a 0.2 um filtered solution of PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
C-Avi-6His
ObservedMW:
35-50 kDa
Purity:
> 95 % as determined by reducing SDS-PAGE.
Sequence:
Thr32-His266
Target Synonym:
Dickkopf-related protein 1;Dickkopf-1;Dkk-1
UNIProt ID:
O94907

Documents