Elabscience

Icam5 Polyclonal Antibody

Product Code:
 
E-AB-66553
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Mouse
  • Rat
Application:
 
Western Blot (WB)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze / thaw cycles.
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Western blot analysis of extracts of Mouse brain using Icam5 Polyclonal Antibody at dilution of 1:1000.
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Western blot analysis of extracts of Mouse brain using Icam5 Polyclonal Antibody at dilution of 1:1000.

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E-AB-66553-60uL60uL£210.00
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E-AB-66553-120uL120uL£291.00
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E-AB-66553-200uL200uL£431.00
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Further Information

Abbreviation:
Icam5
Background:
ICAM-5, also known as telencephalin, is a type I integral membrane glycoprotein of the immunoglobulin superfamily. It is specifically expressed in the postnatal excitatory neuronal cell bodies, dendritic shafts, and dendritic filopodia of the telencephalon. ICAM-5 functions in both the immune and nervous systems. ICAM-5 strongly stimulates neurite outgrowth. It is cleaved by matrix metalloproteases upon activation of glutamate receptors or degraded through endocytosis resulting in increased spine maturation. The cleaved soluble fragment of ICAM-5 is immunosuppressive, which may be important in neuronal inflammatory diseases.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Calculated MW:
96kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000
Immunogen:
Recombinant fusion protein of mouse Icam5 (NP_032345.2).
ObservedMW:
140kDa
Purification method:
Affinity purification
Target Synonym:
ICAM5;TLCN;TLN;Icam5
UNIProt ID:
Q60625

Documents