Elabscience

CMKLR1 Polyclonal Antibody

Product Code:
 
E-AB-66779
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Mouse
  • Rat
Application:
 
Western Blot (WB)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze / thaw cycles.
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Western blot analysis of extracts of Rat heart using CMKLR1 Polyclonal Antibody at dilution of 1:1000.
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Western blot analysis of extracts of Rat heart using CMKLR1 Polyclonal Antibody at dilution of 1:1000.

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E-AB-66779-200uL200uL£431.00
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Further Information

Abbreviation:
CMKLR1
Background:
Receptor for the chemoattractant adipokine chemerin/RARRES2 and for the omega-3 fatty acid derived molecule resolvin E1. Interaction with RARRES2 induces activation of intracellular signaling molecules, such as SKY, MAPK1/3 (ERK1/2), MAPK14/P38MAPK and PI3K leading to multifunctional effects, like, reduction of immune responses, enhancing of adipogenesis and angionesis. Resolvin E1 down-regulates cytokine production in macrophages by reducing the activation of MAPK1/3 (ERK1/2) and NF-kappa-B. Positively regulates adipogenesis and adipocyte metabolism. Acts as a coreceptor for several SIV strains (SIVMAC316, SIVMAC239, SIVMACL7E-FR and SIVSM62A), as well as a primary HIV-1 strain (92UG024-2).
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Calculated MW:
42kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000
Immunogen:
A synthetic peptide of human CMKLR1 (NP_001135815.1).
ObservedMW:
55kDa
Purification method:
Affinity purification
Target Synonym:
CMKLR1;CHEMERINR;ChemR23;DEZ;RVER1
UNIProt ID:
Q99788

Documents