Elabscience

INS Polyclonal Antibody

Product Code:
 
E-AB-67409
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Immunofluorescence (IF)
  • Immunohistochemistry (IHC)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze / thaw cycles.
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Immunohistochemistry of paraffin-embedded Mouse pancreatic islet using INS Polyclonal Antibody at dilution of 1:50 (40x lens).
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Immunohistochemistry of paraffin-embedded Mouse pancreatic islet using INS Polyclonal Antibody at dilution of 1:50 (40x lens).

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E-AB-67409-60uL60uL£210.00
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E-AB-67409-120uL120uL£291.00
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E-AB-67409-200uL200uL£431.00
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Further Information

Abbreviation:
INS
Background:
After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. Alternative splicing results in multiple transcript variants.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:200 IF 1:50-1:200
Immunogen:
Recombinant fusion protein of human INS (NP_000198.1).
Purification method:
Affinity purification
Target Synonym:
IDDM;IDDM1;IDDM2;ILPR;IRDN;MODY10;INS;Insulin;insulin
UNIProt ID:
P01308

Documents