Elabscience

PE Anti-Mouse CD51 Antibody[RMV-7]

Product Code:
 
E-AB-F1235D
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rat
Antibody Isotype:
 
Rat IgG1, κ
Antibody Clone:
 
RMV-7
Regulatory Status:
 
RUO
Target Species:
 
Mouse
Application:
 
Flow Cytometry
Shipping:
 
Ice packs
Storage:
 
Store at 2-8°C and protected from prolonged exposure to light. Do not freeze.
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C57BL/6 murine bone marrow cells are stained with PE Anti-Mouse CD51 Antibody (filled gray histogram). Unstained bone marrow cells (empty black histogram) are used as control.
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C57BL/6 murine bone marrow cells are stained with PE Anti-Mouse CD51 Antibody (filled gray histogram). Unstained bone marrow cells (empty black histogram) are used as control.

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CodeSizePrice
E-AB-F1235D-50Tests50Tests£120.00
Quantity:
E-AB-F1235D-100Tests100Tests£143.00
Quantity:
E-AB-F1235D-100Testsx2100Testsx2£184.00
Quantity:
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This product comes from: China.
Typical lead time: 14-21 working days.
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Further Information

Abbreviation:
CD51
Background:
CD51 is a 140 kD protein, also known as αV integrin, vitronectin receptor, and integrin αV. It is a member of the integrin family, expressed on activated T cells, polymorphonuclear granulocytes, platelets, blastocysts, and osteoclasts. CD51 forms heterodimers by association with integrins β1, β3, β5 or β6; these complexes then act as receptors for multiple extracellular matrix proteins (ECM). The αvintegrin heterodimers have varied functions in development, stimulation/activation and homeostasis. The primary ligands for CD51 complexes are fibronectin, fibrinogen, vitronectin, thrombspondin, von Willebrand factor, and CD31. The RMV-7 antibody has been reported to block binding of CD51 to vitronectin, fibronectin, and CD31 in some cell types, as well as blocking LAK cell cytotoxicity.
Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Concentration:
5 uL/Test
Conjugation:
PE
GeneID:
16410
Target Synonym:
Integrin alpha-V;αV integrin;Vitronectin Receptor;Integrin αV chain;ITGAV;
UNIProt ID:
P43406
Usage:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 uL of antibody per test (million cells in 100 uL staining volume or per 100 uL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

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