Elabscience

PerCP/Cyanine5.5 Anti-Human CD107a/LAMP-1 Antibody[H4A3]

Product Code:
 
E-AB-F1149J
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Mouse
Antibody Isotype:
 
Mouse IgG1, κ
Antibody Clone:
 
H4A3
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Flow Cytometry
Shipping:
 
Ice packs
Storage:
 
Store at 2-8°C and protected from prolonged exposure to light. Do not freeze.
 

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CodeSizePrice
E-AB-F1149J-20Tests20Tests£153.00
Quantity:
E-AB-F1149J-100Tests100Tests£305.00
Quantity:
E-AB-F1149J-100Testsx2100Testsx2£418.00
Quantity:
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Further Information

Abbreviation:
CD107a/LAMP-1
Background:
CD107a, also known as Lysosome-Associated Membrane Protein 1 (LAMP-1) or LGP-120, is a 110-140 kD type I membrane glycoprotein. Mature CD107a is heavily glycosylated from a 40 kD core protein. This molecule is located on the luminal side of lysosomes. Upon activation, CD107a is transferred to the cell membrane surface of activated platelets, activated lymphocytes, macrophages, epithelial cells, endothelial cells, and some tumor cells. CD107a has been suggested to play a role in the protection of lysosomal membrane from lysosomal hydrolases which is involved in cell adhesion and regulation of tumor metastasis, and mediates autoimmune disease progression. CD107a is a ligand for galaptin and E-selectin. Surface expression of LAMP-1 has been shown to correlate with CD8+T cell and NK cell cytotoxicity.
Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Concentration:
5 uL/Test
Conjugation:
PerCP/Cyanine5.5
GeneID:
3916
Target Synonym:
Lysosome-Associated Membrane Protein 1; LGP-120; LAMP-1;
UNIProt ID:
P11279
Usage:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 uL of antibody per test (million cells in 100 uL staining volume or per 100 uL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

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