Elabscience

VGLL1 Polyclonal Antibody

Product Code:
 
E-AB-53198
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze / thaw cycles.
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Western blot analysis of 293T cells using VGLL1 Polyclonal Antibody at dilution of 1:4600
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Western blot analysis of 293T cells using VGLL1 Polyclonal Antibody at dilution of 1:4600

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E-AB-53198-20uL20uL£125.00
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E-AB-53198-120uL120uL£237.00
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E-AB-53198-200uL200uL£344.00
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Further Information

Abbreviation:
VGLL1
Background:
The protein encoded by this gene binds proteins of the TEA domain family of transcription factors (TEFs) through the Vg (vestigial) homology region found in its N-terminus. It may thus function as a specific coactivator for the mammalian TEFs. TDU interacted directly with the TEA domain family member, TEF1, and deletion of the Vg homology region abolished the interaction. The TDU-TEF1 dimer activated a reporter plasmid, and expression of TDU in Drosophila rescued loss of Vg function. The interaction was stronger in cardiac myocytes, suggesting a myocyte-specific factor may participate in the interaction. Vgll1 was weakly active in driving expression of a reporter gene from the mouse skeletal muscle alpha-actin promoter, and Vgll1 could partially reverse the inhibitory effect of TEF1 in this assay.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Calculated MW:
29 kDa
Concentration:
2 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:2000-1:10000 ELISA 1:2000-1:20000
Immunogen:
Synthetic peptide of human VGLL1
ObservedMW:
Refer to figures
Purification method:
Antigen affinity purification
Target Synonym:
Protein TONDU;TDU;TONDU;Transcription cofactor vestigial like protein 1;Transcription cofactor vestigial-like protein 1;Vestigial like 1;vestigial like 1 homolog (Drosophila);Vgl-1;VGL1;Vgll1;VGLL1
UNIProt ID:
Q99990

Documents