Elabscience

ROCK2 Polyclonal Antibody

Product Code:
 
E-AB-52117
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze / thaw cycles.
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Western blot analysis of Mouse brain tissue Rat brain tissue and HepG2 cell lysates using ROCK2 Polyclonal Antibody at dilution of 1:400
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Western blot analysis of Mouse brain tissue Rat brain tissue and HepG2 cell lysates using ROCK2 Polyclonal Antibody at dilution of 1:400

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E-AB-52117-20uL20uL£125.00
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E-AB-52117-60uL60uL£172.00
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E-AB-52117-120uL120uL£237.00
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E-AB-52117-200uL200uL£344.00
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This product comes from: China.
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Further Information

Abbreviation:
ROCK2
Background:
The protein encoded by this gene is a serine/threonine kinase that regulates cytokinesis, smooth muscle contraction, the formation of actin stress fibers and focal adhesions, and the activation of the c-fos serum response element. This protein, which is an isozyme of ROCK1 is a target for the small GTPase Rho. Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. Involved in regulation of smooth muscle contraction, actin cytoskeleton organization, stress fiber and focal adhesion formation, neurite retraction, cell adhesion and motility via phosphorylation of ADD1, BRCA2, CNN1, EZR, DPYSL2, EP300, MSN, MYL9/MLC2, NPM1, RDX, PPP1R12A and VIM. Phosphorylates SORL1 and IRF4.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Calculated MW:
161 kDa
Concentration:
0.78 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, ELISA 1:5000-1:10000
Immunogen:
Fusion protein of human ROCK2
ObservedMW:
Refer to figures
Purification method:
Antigen affinity purification
Target Synonym:
coiled-coil-containing protein kinase 2;KIAA0619;p164 ROCK 2;p164 ROCK-2;Rho associated coiled coil containing protein kinase 2;Rho associated protein kinase 2;Rho associated;coiled coil containing protein kinase II;Rho kinase 2;Rho-associated;Rho-associated protein kinase 2;ROCK 2;Rock II;Rock2;ROCK2;Rock2m;ROK alpha;ROKalpha
UNIProt ID:
O75116

Documents