Elabscience

IL4R Polyclonal Antibody

Product Code:
 
E-AB-52020
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze / thaw cycles.
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Immunohistochemistry of paraffin-embedded Human liver cancer tissue using IL4R Polyclonal Antibody at dilution of 1:45(?200)
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Immunohistochemistry of paraffin-embedded Human tonsil tissue using IL4R Polyclonal Antibody at dilution of 1:45(?200)
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Immunohistochemistry of paraffin-embedded Human liver cancer tissue using IL4R Polyclonal Antibody at dilution of 1:45(?200)
Immunohistochemistry of paraffin-embedded Human tonsil tissue using IL4R Polyclonal Antibody at dilution of 1:45(?200)

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E-AB-52020-20uL20uL£125.00
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E-AB-52020-60uL60uL£172.00
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E-AB-52020-120uL120uL£237.00
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E-AB-52020-200uL200uL£344.00
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Further Information

Abbreviation:
IL4R
Background:
This gene encodes the alpha chain of the interleukin-4 receptor, a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to regulate IgE production. The encoded protein also can bind interleukin 4 to promote differentiation of Th2 cells. A soluble form of the encoded protein can be produced by proteolysis of the membrane-bound protein, and this soluble form can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells. Allelic variations in this gene have been associated with atopy, a condition that can manifest itself as allergic rhinitis, sinusitus, asthma, or eczema. Polymorphisms in this gene are also associated with resistance to human immunodeficiency virus type-1 infection. Alternate splicing results in multiple transcript variants.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Concentration:
1.26 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:30-1:150, ELISA 1:5000-1:10000
Immunogen:
Synthetic peptide of human IL4R
Purification method:
Antigen affinity purification
Target Synonym:
CD124;IL 4R alpha;IL-4 receptor subunit alpha;IL-4-binding protein;IL-4R subunit alpha;IL-4R-alpha;IL-4RA;IL4-BP;Il4r;IL4R nirs variant 1;IL4RA;IL4RA;Interleukin 4 receptor alpha chain;Interleukin 4 receptor;sIL4Ralpha/prot;Soluble IL-4 receptor subunit alpha;Soluble IL-4R-alpha;Soluble interleukin-4 receptor subunit alpha
UNIProt ID:
P24394

Documents