Elabscience

JPT1 Polyclonal Antibody

Product Code:
 
E-AB-18906
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze / thaw cycles.
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Immunohistochemistry of paraffin-embedded Human tonsil tissue using JPT1 Polyclonal Antibody at dilution of 1:35(?200)
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Immunohistochemistry of paraffin-embedded Human breast cancer tissue using JPT1 Polyclonal Antibody at dilution of 1:35(?200)
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Immunohistochemistry of paraffin-embedded Human tonsil tissue using JPT1 Polyclonal Antibody at dilution of 1:35(?200)
Immunohistochemistry of paraffin-embedded Human breast cancer tissue using JPT1 Polyclonal Antibody at dilution of 1:35(?200)

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E-AB-18906-20uL20uL£125.00
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E-AB-18906-120uL120uL£237.00
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E-AB-18906-200uL200uL£344.00
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Further Information

Abbreviation:
JPT1
Background:
Modulates negatively AKT-mediated GSK3B signaling (PubMed:21323578, PubMed:22155408). Induces CTNNB1 'Ser-33' phosphorylation and degradation through the suppression of the inhibitory 'Ser-9' phosphorylation of GSK3B, which represses the function of the APC:CTNNB1:GSK3B complex and the interaction with CDH1/E-cadherin in adherent junctions (PubMed:25169422). Plays a role in the regulation of cell cycle and cell adhesion (PubMed:25169422, PubMed:25450365). Has an inhibitory role on AR-signaling pathway through the induction of receptor proteosomal degradation (PubMed:22155408).
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Concentration:
0.6 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:40-1:200, ELISA 1:5000-1:10000
Immunogen:
Fusion protein of human JPT1
Purification method:
Antigen affinity purification
Target Synonym:
Androgen regulated protein 2;Androgen-regulated protein 2;ARM2;Hematological and neurological expressed 1;Hematological and neurological expressed 1 protein;HN1;HN1;HN1A
UNIProt ID:
Q9UK76

Documents