Elabscience

HLA-DRB5 Polyclonal Antibody

Product Code:
 
E-AB-18660
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze / thaw cycles.
1 / 1
Immunohistochemistry of paraffin-embedded Human liver cancer tissue using HLA-DRB5 Polyclonal Antibody at dilution of 1:45(?200)
❮❯

Immunohistochemistry of paraffin-embedded Human liver cancer tissue using HLA-DRB5 Polyclonal Antibody at dilution of 1:45(?200)

No additional charges, what you see is what you pay! *

CodeSizePrice
E-AB-18660-20uL20uL£125.00
Quantity:
E-AB-18660-60uL60uL£172.00
Quantity:
E-AB-18660-120uL120uL£237.00
Quantity:
E-AB-18660-200uL200uL£344.00
Quantity:
Prices exclude any Taxes / VAT
How to order with us   Contact us
Stay in control of your spending. These prices have no additional charges, not even shipping!
* Rare exceptions are clearly labelled (only 0.14% of items!).
Multibuy discounts available! Contact us to find what you can save.
This product comes from: China.
Typical lead time: 14-21 working days.
Contact us for more accurate information.
  • Further Information
  • Documents
  • Show All

Further Information

Abbreviation:
HLA-DRB5
Background:
HLA-DRB5 belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DRA) and a beta (DRB) chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. Within the DR molecule the beta chain contains all the polymorphisms specifying the peptide binding specificities. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. DRB1 is expressed at a level five times higher than its paralogues DRB3, DRB4 and DRB5. The presence of DRB5 is linked with allelic variants of DRB1, otherwise it is omitted. There are 4 related pseudogenes: DRB2, DRB6, DRB7, DRB8 and DRB9.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Concentration:
1.62 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:40-1:200, ELISA 1:5000-1:10000
Immunogen:
Fusion protein of human HLA-DRB5
Purification method:
Antigen affinity purification
Target Synonym:
DR 9;DR beta 5;DR beta 5 chain;DR beta-5;DR beta5;DR2 beta 2;DR2-beta-2;DR9;DRB5;Dw2;FLJ76359;HLA class II histocompatibility antigen;HLA class II histocompatibility antigen DR beta 5 chain;HLA class II histocompatibility antigen DRB1-9 beta chain;HLA class II histocompatibility antigen; DR-5 beta chain;HLA DRB;HLA-DRB5;Human leucocyte antigen DRB5;Leukocyte antigen class II;Major histocompatibility complex; class II; DR beta 51;MHC class II antigen DRB1*9;MHC class II antigen DRB5;MHC class II HLA beta chain;MHC HLA-DR-beta cell surface glycoprotein;MHC HLA-DR-beta chain
UNIProt ID:
Q30154

Documents