Elabscience

Recombinant Mouse TRAIL R2/TNFRSF10B Protein (AVI & His Tag)

Product Code:
 
PKSM041369
Product Group:
 
Recombinant Proteins
Supplier:
 
Elabscience
Host Type:
 
Mouse
Regulatory Status:
 
RUO
Shipping:
 
This product is provided as lyophilized powder which is shipped with ice packs.
Storage:
 
Generally lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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CodeSizePrice
PKSM041369-20ug20ug£351.00
Quantity:
PKSM041369-100ug100ug£819.00
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This product comes from: China.
Typical lead time: 14-21 working days.
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Further Information

Abbreviation:
TRAIL R2;TNFRSF10B
Accession:
Q9QZM4
Background:
Mouse tumor necrosis factor receptor superfamily member 10B (TNFRSF10B) is a member of the TNFR family which contains 1 death domain and 3 TNFR-Cys repeats. TNFRSF10B exhibits high structural and functional homology to TRAIL-R1 (DR-4). TNFRSF10B is highly expressed in heart, lung, lymphocytes, spleen and kidney. In addition, it is regulated by the tumor suppressor p53. TNFRSF10B is the receptor for the cytotoxic ligand TNFSF10/TRAIL. It promotes the activation of NF-kappa-B and is essential for ER stress-induced apoptosis. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases mediating apoptosis.
Calculated MW:
16.4 kDa
Conjugation:
Biotinylated
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
HEK293 Cells
Formulation:
Lyophilized from a 0.2 um filtered solution of PBS, pH7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
C-Avi-His
ObservedMW:
20-40 kDa
Purity:
> 95 % as determined by reducing SDS-PAGE.
Sequence:
Asn53-Ser177
Target Synonym:
Tumor Necrosis Factor Receptor Superfamily Member 10B;Death Receptor 5;TNF-Related Apoptosis-Inducing Ligand Receptor 2;TRAIL Receptor 2;TRAIL-R2;CD262;TNFRSF10B;DR5;KILLER;TRAILR2;TRICK2;ZTNFR9
UNIProt ID:
Q9QZM4

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