Elabscience

Recombinant Human CTLA4 Protein (Fc & Avi Tag)(Active)

Product Code:
 
PKSH033803
Product Group:
 
Recombinant Proteins
Supplier:
 
Elabscience
Host Type:
 
Human
Regulatory Status:
 
RUO
Application:
 
Enzyme-Linked Immunosorbent Assay (ELISA)
Shipping:
 
This product is provided as lyophilized powder which is shipped with ice packs.
Storage:
 
Generally lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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CodeSizePrice
PKSH033803-20ug20ug£351.00
Quantity:
PKSH033803-100ug100ug£819.00
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This product comes from: China.
Typical lead time: 14-21 working days.
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Further Information

Abbreviation:
CTLA4
Accession:
P16410
Activity:
Immobilized Human CTLA-4-Fc-Avi at 2ug/ml(100 ul/well) can bind Human B7-2-6His(Cat: PKSH033722). The ED50 of Human CTLA-4-Fc-Avi is 1. 98 ug/mL
Background:
Cytotoxic T-lymphocyte protein 4; is a single-pass type I membrane protein. It is widely expressed with highest levels in lymphoid tissues. CD28 and CTLA-4; together with their ligands; B7-1 and B7-2; constitute one of the dominant costimulatory pathways that regulate T and B cell responses. CD28 and CTLA-4 are structurally homologous molecules that are members of the immunoglobulin (Ig) gene superfamily. CTLA4 transmits an inhibitory signal to T cells; whereas CD28 transmits a stimulatory signal. Intracellular CTLA4 is also found in regulatory T Cells and may play an important role in their functions. Tcell activation through the Tcell receptor and CD28 leads to increased expression of CTLA4.
Calculated MW:
41.5 kDa
Conjugation:
Biotinylated
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
HEK293 Cells
Formulation:
Lyophilized from a 0.2 um filtered solution of PBS, pH7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
C-Fc-Avi
ObservedMW:
57-60 kDa
Purity:
> 95 % as determined by reducing SDS-PAGE.
Sequence:
Lys36-Asp161
Target Synonym:
Cytotoxic T-lymphocyte protein 4;Cytotoxic T-lymphocyte-associated antigen 4;CTLA4;CD152;Cytotoxic T-Lymphocyte-Associated Protein 4
UNIProt ID:
P16410

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