Elabscience

Recombinant Human ROR1 Protein (His & Avi Tag)

Product Code:
 
PKSH033794
Product Group:
 
Recombinant Proteins
Supplier:
 
Elabscience
Host Type:
 
Human
Regulatory Status:
 
RUO
Shipping:
 
This product is provided as lyophilized powder which is shipped with ice packs.
Storage:
 
Generally lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
 

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CodeSizePrice
PKSH033794-20ug20ug£351.00
Quantity:
PKSH033794-100ug100ug£819.00
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This product comes from: China.
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Further Information

Abbreviation:
ROR1
Accession:
Q01973
Background:
Receptor tyrosine kinase-like orphan receptor 1 (ROR1); also known as neurotrophic tyrosine kinase; it is a member of the ROR family within receptor tyrosine kinases (RTK) superfamily. Human ROR1 is a type I transmembrane protein with 937 amino acids (aa) in length. It contains a 29 aa signal sequence; a 377 aa extracellular domain (ECD); a 21 aa transmembrane segment; and a 510 aa cytoplasmic region. ROR1 expressed strongly in human heart; lung and kidney; but weakly in the CNS. At developmental stage; it expressed at high levels during early embryonic development. ROR1 has been shown to have very low kinase activity in vitro and is unlikely to function as a tyrosine kinase in vivo. It may act as a receptor for wnt ligand WNT5A which may result in the inhibition of WNT3A-mediated signaling.
Calculated MW:
44.6 kDa
Conjugation:
Biotinylated
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
HEK293 Cells
Formulation:
Lyophilized from a 0.2 um filtered solution of PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
C-His-Avi
ObservedMW:
55-80 kDa
Purity:
> 95 % as determined by reducing SDS-PAGE.
Sequence:
Gln30-Glu403
Target Synonym:
Inactive tyrosine-protein kinase transmembrane receptor ROR1;Neurotrophic tyrosine kinase;receptor-related 1;ROR1;NTRKR1
UNIProt ID:
Q01973

Documents