Elabscience

Recombinant Rat PD-L1/B7-H1/CD274 Protein (C-His)

Product Code:
 
PKSR030458
Product Group:
 
Recombinant Proteins
Supplier:
 
Elabscience
Host Type:
 
Rat
Regulatory Status:
 
RUO
Shipping:
 
This product is provided as lyophilized powder which is shipped with ice packs.
Storage:
 
Generally lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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CodeSizePrice
PKSR030458-10ug10ug£166.00
Quantity:
PKSR030458-50ug50ug£315.00
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This product comes from: China.
Typical lead time: 14-21 working days.
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Further Information

Abbreviation:
PD-L1;B7-H1;CD274
Accession:
D4AE25
Background:
CD274, also known as B7-H1 or programmed death ligand 1 (PD-L1), is a 40 kD type I transmembrane protein and a member of the B7 family within the immunoglobulin receptor superfamily. Programmed death-1 ligand-1 (PD-L1, CD274, B7-H1) has been identified as the ligand for the immunoinhibitory receptor programmed death-1(PD1/PDCD1) and has been demonstrated to play a role in the regulation of immune responses and peripheral tolerance. By binding to PD1 on activated T-cells and B-cells, PD-L1 may inhibit ongoing T-cell responses by inducing apoptosis and arresting cell-cycle progression. Accordingly, it leads to growth of immunogenic tumor growth by increasing apoptosis of antigen specific T cells and may contribute to immune evasion by cancers. PD-L1 thus is regarded as promising therapeutic target for human autoimmune disease and malignant cancers.
Calculated MW:
26.1 kDa
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
HEK293 Cells
Formulation:
Lyophilized from a 0.2 um filtered solution of PBS, pH7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
C-His
ObservedMW:
40-60 kDa
Purity:
> 95 % as determined by reducing SDS-PAGE.
Sequence:
Ala18-Thr238
Target Synonym:
B7-H;B7-H1;B7H1;PD-L1;PDCD1L1;PDCD1LG1;PDL1
UNIProt ID:
D4AE25

Documents