Elabscience

Recombinant Rat HER2/ErbB2 Protein (aa 67-323, His Tag)

Product Code:
 
PKSR030455
Product Group:
 
Recombinant Proteins
Supplier:
 
Elabscience
Host Type:
 
Rat
Regulatory Status:
 
RUO
Shipping:
 
This product is provided as lyophilized powder which is shipped with ice packs.
Storage:
 
Generally lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
 

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CodeSizePrice
PKSR030455-10ug10ug£170.00
Quantity:
PKSR030455-50ug50ug£315.00
Quantity:
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This product comes from: China.
Typical lead time: 14-21 working days.
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Further Information

Abbreviation:
HER2;ErbB2
Accession:
P06494
Background:
ERBB2 belongs to the protein kinase superfamily, Tyr protein kinase family and EGF receptor subfamily. It contains a protein kinase domain. ERBB2 is widely expressed in epithelial cells, and amplification and/or overexpression of ErbB2 has been reported associated with malignancy and a poor prognosis in numerous carcinomas, including breast, prostate and ovarian cancers. Rat ERBB2 is an essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone. ErbB2 mediates signalling pathways which involve mitogen-activated protein kinase and phosphatidylinositol-3 kinase, this receptor plays a key role in development, cell proliferation and differentiation.
Calculated MW:
29.3 kDa
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
E.coli
Formulation:
Lyophilized from a 0.2 um filtered solution of 20mM Tris,150mM NaCl, 4M Urea, pH 8.0.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
C-6His
ObservedMW:
32 kDa
Purity:
> 95 % as determined by reducing SDS-PAGE.
Sequence:
Ala67-Val323
Target Synonym:
Receptor tyrosine-protein kinase erbB-2;Epidermal growth factor receptor-related protein;Proto-oncogene Neu;Proto-oncogene c-ErbB-2;p185erbB2;p185neu;CD340;ERBB2;ENV;ENVW;ERVWE1;HER-2;HER-2/neu;HER2;HERV-7q;HERV-W-ENV;HERV7Q;HERVW;HERVWENV;MLN 19;MLN19
UNIProt ID:
P06494

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