Elabscience

Recombinant Cynomolgus LAG-3/CD223 Protein (Fc Tag)

Product Code:
 
PKSQ050015
Product Group:
 
Recombinant Proteins
Supplier:
 
Elabscience
Host Type:
 
Monkey
Regulatory Status:
 
RUO
Shipping:
 
This product is provided as lyophilized powder which is shipped with ice packs.
Storage:
 
Generally lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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CodeSizePrice
PKSQ050015-10ug10ug£219.00
Quantity:
PKSQ050015-50ug50ug£497.00
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This product comes from: China.
Typical lead time: 14-21 working days.
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Further Information

Abbreviation:
LAG-3;CD223
Accession:
XP_005570011.1
Background:
Human Lymphocyte activation gene 3 protein( LAG3) is a member of immunoglobulin (Ig) superfamily. LAG3 contains 4 extracellular Ig-like domains. The LAG3 gene contains 8 exons. LAG3 is involved in lymphocyte activation and can bind to HLA class-II antigens. It is selectively expressed in activated T and NK cells. LAG3 has a negative regulatory function in T cells and acts as as a new marker of T cell induced B cell activation. As a soluble molecule, LAG3 activates antigen-presenting cells through MHC class II signaling. It can lead to increased antigen-specific T-cell responses in vivo. LAG-3 has higher affinity to MHC class II than CD4.
Calculated MW:
73.6 kDa
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
HEK293 Cells
Formulation:
Lyophilized from a 0.2 um filtered solution ofPBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
C-Fc
ObservedMW:
90 kDa
Purity:
> 90 % as determined by reducing SDS-PAGE.
Sequence:
Ala18-His449(Pro74)
Target Synonym:
Lymphocyte activation gene 3 protein;LAG3;LAG-3;Protein FDC;CD223

Documents