Elabscience

Recombinant Cynomolgus CRTAM/CD355 Protein (His Tag)

Product Code:
 
PKSQ050013
Product Group:
 
Recombinant Proteins
Supplier:
 
Elabscience
Host Type:
 
Monkey
Regulatory Status:
 
RUO
Shipping:
 
This product is provided as lyophilized powder which is shipped with ice packs.
Storage:
 
Generally lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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CodeSizePrice
PKSQ050013-10ug10ug£180.00
Quantity:
PKSQ050013-50ug50ug£378.00
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This product comes from: China.
Typical lead time: 14-21 working days.
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Further Information

Abbreviation:
CRTAM;CD355
Accession:
A0A2K5TKL4
Background:
Cytotoxic and Regulatory T-Cell Molecule (CRTAM) is a member of Nectin family under the immunoglobulin superfamily that is expressed by activated CD8+ and NK T cells. CRTAM is found in spleen, thymus, small intestine, peripheral blood, and it is highly expressed by Purkinje cells of the cerebellum. CRTAM is a type I transmembrane glycoprotein containing one Ig-like C2-type domain and one Ig-like V-type domain in its extracellular domain, while its cytoplasmic region shows a potential class I PDZ domain. CRTAM is expressed as a homodimer on the cell surface but does not show homotypic binding in trans. The high affinity of CRTAM/IGSF4 adhesion allows CRTAM to disrupt IGSF4 homotypic interactions. IGSF4 and T cell receptor coengagement of CD8+ cells expressiong CRTAM induces increased IFNγ or IL-22 production.
Calculated MW:
30.8 kDa
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
HEK293 Cells
Formulation:
Lyophilized from a 0.2 um filtered solution of PBS,pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
C-His
ObservedMW:
50-60 kDa
Purity:
> 95 % as determined by reducing SDS-PAGE.
Sequence:
Ser18-Gly287
Target Synonym:
Cytotoxic and Regulatory T-Cell Molecule;Class-I MHC-Restricted T-Cell-Associated Molecule;CD355;CRTAM
UNIProt ID:
A0A2K5TKL4

Documents