Elabscience

Recombinant Human CD40L/TNFSF5 Protein (E.coli)(Active)

Product Code:
 
PKSH033725
Product Group:
 
Recombinant Proteins
Supplier:
 
Elabscience
Host Type:
 
Human
Regulatory Status:
 
RUO
Application:
 
Enzyme-Linked Immunosorbent Assay (ELISA)
Shipping:
 
This product is provided as lyophilized powder which is shipped with ice packs.
Storage:
 
Generally lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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CodeSizePrice
PKSH033725-20ug20ug£210.00
Quantity:
PKSH033725-100ug100ug£472.00
Quantity:
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This product comes from: China.
Typical lead time: 14-21 working days.
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Further Information

Abbreviation:
CD40L;TNFSF5
Accession:
P29965
Activity:
Immobilized Human CD40L at 5ug/ml(100 ul/well) can bind Human CD40-Fc(Cat: PKSH032216). The ED50 of Human CD40L is 68.55ug/ml.
Background:
CD40 Ligand (CD40LG) is a type II transmembrane glycoprotein that belongs to the TNF superfamily. Like other TNF superfamily members; CD40LG exists as a trimer in membrane bound and soluble form; both of which are bioactive. CD40LG is a ligand for CD40; its ligation also initiates signal transduction in CD40LG expressing cells. CD40LG is a differentiation antigen that is expressed on the surface of T-cells. It stimulates B-cell proliferation and secretion of all immunoglobulin isotypes in the presence of cytokines. CD40LG has been shown to induce cytokine production and tumoricidal activity in peripheral blood monocytes. It also co-stimulates proliferation of activated T-cells and this is accompanied by the production of IFN-gamma; TNF-alpha; and IL2.
Calculated MW:
16.2 kDa
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
E.coli
Formulation:
Lyophilized from a 0.2 um filtered solution of 20mM PB, 200mM NaCl, 0.1mM EDTA, pH 7.0.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
None
ObservedMW:
15 kDa
Purity:
> 95 % as determined by reducing SDS-PAGE.
Sequence:
Met113-Leu261
Target Synonym:
CD40 Ligand;CD40-L;T-Cell Antigen Gp39;TNF-Related Activation Protein;TRAP;Tumor Necrosis Factor Ligand Superfamily Member 5;CD154;CD40LG;CD40L;TNFSF5;TRAP;hCD40L;HIGM1;IGM;IMD3;T-BAM;TNFSF5;TRAP
UNIProt ID:
P29965

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