Elabscience

Recombinant Human CD16b/FCGR3B Protein (aa 17-208, His Tag)

Product Code:
 
PKSH033599
Product Group:
 
Recombinant Proteins
Supplier:
 
Elabscience
Host Type:
 
Human
Regulatory Status:
 
RUO
Shipping:
 
This product is provided as lyophilized powder which is shipped with ice packs.
Storage:
 
Generally lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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CodeSizePrice
PKSH033599-10ug10ug£180.00
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PKSH033599-50ug50ug£378.00
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This product comes from: China.
Typical lead time: 14-21 working days.
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Further Information

Abbreviation:
CD16b;FCGR3B
Accession:
O75015
Background:
Low affinity immunoglobulin gamma Fc region receptor III-B; also known as Fc-gamma RIII-beta; FcR-10; IgG Fc receptor III-1; FCG3; FCGR3; CD16b and FCGR3B. FCGR3B is a GPI-anchor membrane protein and contains two Ig-like C2 type domains. FCGR3B can be expressed in orphonuclear leukocytes and stimulated eosinophils. FCGR3B can interact with INPP5D/SHIP1. FCGR3B localizes in the FCGR gene cluster is a CN polymorphic gene involved in the recruitment of polymorphonuclear neutrophils to sites of inflammation and their activation. FCGR3B may serve as a trap for immune complexes in the peripheral circulation which does not activate neutrophils.
Calculated MW:
22.7 kDa
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
HEK293 Cells
Formulation:
Lyophilized from a 0.2 um filtered solution of PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
C-His
ObservedMW:
35-65 kDa
Purity:
> 95 % as determined by reducing SDS-PAGE.
Sequence:
Gly17-Gln208
Target Synonym:
Low affinity immunoglobulin gamma Fc region receptor III-B;Fc-gamma RIII-beta;FcR-10;IgG Fc receptor III-1;FCG3;FCGR3;CD16b and FCGR5B;FCRIII;FCRIIIb
UNIProt ID:
O75015

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