Elabscience

Recombinant Human TrkB/NTRK2 Protein (His Tag)(Active)

Product Code:
 
PKSH033579
Product Group:
 
Recombinant Proteins
Supplier:
 
Elabscience
Host Type:
 
Human
Regulatory Status:
 
RUO
Application:
 
Enzyme-Linked Immunosorbent Assay (ELISA)
Shipping:
 
This product is provided as lyophilized powder which is shipped with ice packs.
Storage:
 
Generally lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
 

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CodeSizePrice
PKSH033579-10ug10ug£116.00
Quantity:
PKSH033579-50ug50ug£195.00
Quantity:
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This product comes from: China.
Typical lead time: 14-21 working days.
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Further Information

Abbreviation:
TrkB;NTRK2
Accession:
Q16620
Activity:
Immobilized Human NT-3(Cat: PKSH032803) at 2ug/ml(100 ul/well) can bind Human TrkB-His. The ED50 of Human TrkB-His is 3. 777ug/ml.
Background:
The TRK Family of Tyrosine Kinase Receptor consists of 3 members: TrkA, TrkB and TrkC. The three TRK family proteins have different ligand specificities. They connect to different neurotrophins, including NGF, BDNF, NT-3NT-4/5. TRKA binds NGF, TRKB binds BDNF and NT-3, TRKC binds NT-4/5. At the protein sequence level, human and rat TRKB have greater than 90% sequence identity and the proteins exbihit cross-species activity. TRKB is primarily expressed in the nervous system and it also expression in a wide variety of tissues with low levels.
Calculated MW:
45.25 kDa
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
HEK293 Cells
Formulation:
Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.2.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
C-His
ObservedMW:
60-105 kDa
Purity:
> 95 % as determined by reducing SDS-PAGE.
Sequence:
Cys32-His430
Target Synonym:
BDNF/NT-3 Growth Factors Receptor;GP145-TrkB;Trk-B;Neurotrophic Tyrosine Kinase Receptor Type 2;TrkB Tyrosine Kinase;Tropomyosin-Related Kinase B;NTRK2;TRKB
UNIProt ID:
Q16620

Documents