Elabscience

Recombinant Human PDGFRa/CD140a Protein (His Tag)

Product Code:
 
PKSH033564
Product Group:
 
Recombinant Proteins
Supplier:
 
Elabscience
Host Type:
 
Human
Regulatory Status:
 
RUO
Shipping:
 
This product is provided as lyophilized powder which is shipped with ice packs.
Storage:
 
Generally lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
 

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CodeSizePrice
PKSH033564-10ug10ug£150.00
Quantity:
PKSH033564-50ug50ug£292.00
Quantity:
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This product comes from: China.
Typical lead time: 14-21 working days.
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Further Information

Abbreviation:
PDGFRa;CD140a
Accession:
P16234
Background:
Platelet-derived Growth Factor Receptor Alpha (PDGF Rα) is an enzyme that belongs to the class III subfamily of receptor tyrosine kinases.It is a type I transmembrane glycoprotein, and can form homo- or hetero-dimeric receptors when engaged by dimers of the PDGF family of growth factors, PDGF Rα is strongly expressed in oligodendrocyte, lung, skin and intestinal progenitor cells and induced by inflammation or growth in culture, but is lowly expressed in most mesenchymal cells. PDGF Rα autophosphorylates upon dimerization, activating signaling cascades in PI-3kinase Ras-MAP kinase, and PLC-γ pathways. PDGF Rα has infulence on local gradients of epithelially produced PDGF-AA or PDGF-CC during formation of the cranial ,cardiac neural crest and interstitial kidney mesenchyme.
Calculated MW:
57 kDa
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
HEK293 Cells
Formulation:
Lyophilized from a 0.2 um filtered solution of PBS, pH7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
C-His
ObservedMW:
93 kDa
Purity:
> 95 % as determined by reducing SDS-PAGE.
Sequence:
Gln24-Glu524
Target Synonym:
CD140A;PDGFR-2;PDGFR2;RHEPDGFRA;Platelet-derived growth factor receptor alpha;PDGFR-alpha;Alpha platelet-derived growth factor receptor;CD140 antigen-like family member A;Platelet-derived growth factor alpha receptor;Platelet-derived growth factor receptor 2
UNIProt ID:
P16234

Documents