Elabscience

Recombinant Human Vaspin/SerpinA12 Protein (GST Tag)

Product Code:
 
PKSH033534
Product Group:
 
Recombinant Proteins
Supplier:
 
Elabscience
Host Type:
 
Human
Regulatory Status:
 
RUO
Shipping:
 
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt store it immediately at < -20°C.
Storage:
 
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
 

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CodeSizePrice
PKSH033534-10ug10ug£297.00
Quantity:
PKSH033534-50ug50ug£498.00
Quantity:
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Further Information

Abbreviation:
Vaspin;SerpinA12
Accession:
Q8IW75
Background:
Vaspin (Visceral Adipose-Specific SERPIN) is a newly described adipokine. Vaspin has three β-sheets; nine α-helices; and one central loop; the structure is part of the set of distinctive features that are descriptive of Serpin family members. Vaspin is also a unique insulin sensitizing adipocytokine in obesity. A recent publication indicates that Vaspin mRNA expression in visceral fat is positively correlated with BMI and percent of body fat. and could be associated with parameters of obesity; insulin resistance; and glucose metabolism. These findings suggest a potential clinical use for Vaspin in ameliorating certain aberrations seen in the obesity metabolic syndrome.
Calculated MW:
71.4 kDa
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
E.coli
Formulation:
Supplied as a 0.2 um filtered solution of 50mM Tris-HCl, 160mM NaCl, 0.2mM PMSF, 1mM DTT, 10% Glycerine, pH 7.2 .
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
N-GST
ObservedMW:
72 kDa
Purity:
> 90 % as determined by reducing SDS-PAGE.
Sequence:
Leu21-Lys414
Target Synonym:
Serpin A12;OL-64;Visceral Adipose Tissue-Derived Serine Protease Inhibitor;Vaspin;Visceral Adipose-Specific Serpin;SERPINA12
UNIProt ID:
Q8IW75

Documents