Elabscience

Recombinant Human Cyclophilin A Protein

Product Code:
 
PKSH033420
Product Group:
 
Recombinant Proteins
Supplier:
 
Elabscience
Host Type:
 
Human
Regulatory Status:
 
RUO
Shipping:
 
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt store it immediately at < -20°C.
Storage:
 
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
 

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CodeSizePrice
PKSH033420-10ug10ug£226.00
Quantity:
PKSH033420-50ug50ug£283.00
Quantity:
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This product comes from: China.
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Further Information

Abbreviation:
Cyclophilin A
Accession:
P62937
Background:
Peptidyl-prolyl cis-trans isomerase A is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family; which catalyzes the cis-trans isomerization of proline imidic peptide bonds. Cyclophilin A regulate many biological processes; including intracellular signaling; transcription; inflammation; and apoptosis. Cyclophilin is also incorporated into many viruses; including HIV1; where it has been speculated to be involved in functions such as viral assembly and infectivity. The immunosuppressive activity of cyclosporins has been correlated with their ability to form complexes with cyclophilins that inhibit calcineurin phosphatase activity and prevent incorporation of cyclophilin into viral particles. The cyclosporin/cyclophilin complex selectively binds and inactivates calcineurin; making it a useful inhibitor for studying calcineurin activity.
Calculated MW:
18 kDa
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
E.coli
Formulation:
Supplied as a 0.2 um filtered solution of PBS, 10% Glycerol, pH7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
None
ObservedMW:
16 kDa
Purity:
> 95 % as determined by reducing SDS-PAGE.
Sequence:
Met 1-Glu165
Target Synonym:
Peptidyl-prolyl cis-trans isomerase A;PPIase A;Cyclophilin A;Cyclosporin A-binding protein;Rotamase A;SP18;PPIA;CYPA
UNIProt ID:
P62937

Documents