Elabscience

Recombinant Human FOLR1 Protein (His Tag)

Product Code:
 
PKSH033374
Product Group:
 
Recombinant Proteins
Supplier:
 
Elabscience
Host Type:
 
Human
Regulatory Status:
 
RUO
Shipping:
 
This product is provided as lyophilized powder which is shipped with ice packs.
Storage:
 
Generally lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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CodeSizePrice
PKSH033374-10ug10ug£170.00
Quantity:
PKSH033374-50ug50ug£315.00
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This product comes from: China.
Typical lead time: 14-21 working days.
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Further Information

Abbreviation:
FOLR1
Accession:
NP_057937.1
Background:
Folate receptor alpha(FOLR) belongs to the folate receptor family; and is primarily expressed in tissues of epithelial origin. It is also expressed in kidney; lung and cerebellum. The secreted form is derived from the membrane-bound form either by cleavage of the GPI anchor; or/and by proteolysis catalyzed by a metalloprotease. FOLR1 binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells. It has high affinity for folate and folic acid analogs at neutral pH. Exposure to slightly acidic pH after receptor endocytosis triggers a conformation change that strongly reduces its affinity for folates and mediates their release. It is required for normal embryonic development and normal cell proliferation.
Calculated MW:
25.7 kDa
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
HEK293 Cells
Formulation:
Lyophilized from a 0.2 um filtered solution of PBS, pH7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
C-6His
ObservedMW:
35 kDa
Purity:
> 95 % as determined by reducing SDS-PAGE.
Sequence:
Arg25-Ser234
Target Synonym:
Folate receptor alpha;FR-alpha;Adult folate-binding protein;FBP;Folate receptor 1;Folate receptor;Ovarian tumor-associated antigen MOv18;FOLR1;FBP;Folate Binding Protein;FOLR

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