Elabscience

Recombinant Human Butyrylcholinesterase/BCHE Protein (His Tag)

Product Code:
 
PKSH033346
Product Group:
 
Recombinant Proteins
Supplier:
 
Elabscience
Host Type:
 
Human
Regulatory Status:
 
RUO
Shipping:
 
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt store it immediately at < -20°C.
Storage:
 
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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CodeSizePrice
PKSH033346-10ug10ug£256.00
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PKSH033346-50ug50ug£553.00
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This product comes from: China.
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Further Information

Abbreviation:
Butyrylcholinesterase;BCHE
Accession:
NP_000046.1
Background:
Butyrylcholine Esterase (BCHE) is a secreted protein that belongs to the type-B carboxylesterase/lipase family. BCHE is a major acetylcholine hydrolyzing enzyme in the circulation. It is detected in blood plasma and present in most cells except erythrocytes. BCHE is an esterase with broad substrate specificity. BCHE can contribute to the inactivation of the neurotransmitter acetylcholine. BCHE can degrade a large number of neurotoxic organophosphate esters. Thus, it plays important pharmacological and toxicological roles and is thought to be involved in the pathological progression. Defects in BCHE are the cause of butyrylcholinesterase deficiency (BChE deficiency) which is a metabolic disorder characterized by prolonged apnoea after the use of certain anesthetic drugs, including the muscle relaxants succinylcholine and other ester local anesthetics.
Calculated MW:
66.1 kDa
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
HEK293 Cells
Formulation:
Supplied as a 0.2 um filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 7.5.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
C-6His
ObservedMW:
90 kDa
Purity:
> 95 % as determined by reducing SDS-PAGE.
Sequence:
Glu29-Leu602
Target Synonym:
Cholinesterase;Acylcholine Acylhydrolase;Butyrylcholine Esterase;Choline Esterase II;Pseudocholinesterase;BCHE;CHE1

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