Elabscience

Recombinant Human KIR2DL3 Protein (His Tag)

Product Code:
 
PKSH033319
Product Group:
 
Recombinant Proteins
Supplier:
 
Elabscience
Host Type:
 
Human
Regulatory Status:
 
RUO
Shipping:
 
This product is provided as lyophilized powder which is shipped with ice packs.
Storage:
 
Generally lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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CodeSizePrice
PKSH033319-10ug10ug£170.00
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PKSH033319-50ug50ug£315.00
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This product comes from: China.
Typical lead time: 14-21 working days.
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Further Information

Abbreviation:
KIR2DL3
Accession:
AAX23102.1
Background:
Killer-Cell Immunoglobulin-Like Receptors (KIRs) are important cells of the immune system. KIRs are a family of Natural Killer (NK) Cells surface glycoproteins. KIRs control the killing function of these cells by interacting with MHC class I molecules. This interaction allows KIRs to identify virally infected cells or tumor cells by the distinctive low level of Class I MHC on their surface. The majority of KIRs are inhibitory, their recognition of MHC suppresses the cytotoxic activity of their NK cell. Only a limited number of KIRs have the capacity to activate cells. KIR2DL3 is an inhibitory Killer Cell Ig-like Receptor. KIR2DL3 recognizes class I MHC molecules (HLA-Cw1, -Cw3, -Cw7, and Cw8). KIR2DL3 inhibits the activity of NK cells thus preventing cell lysis.
Calculated MW:
25.4 kDa
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
HEK293 Cells
Formulation:
Lyophilized from a 0.2 um filtered solution of PBS, pH7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
C-6His
ObservedMW:
35-50 kDa
Purity:
> 95 % as determined by reducing SDS-PAGE.
Sequence:
His22-His245
Target Synonym:
Killer Cell Immunoglobulin-Like Receptor 2DL3;CD158 Antigen-Like Family Member B2;KIR-023GB;Killer Inhibitory Receptor cl 2-3;MHC Class I NK Cell Receptor;NKAT2a;NKAT2b;Natural Killer-Associated Transcript 2;NKAT-2;p58 Natural Killer Cell Receptor Clone CL-6;p58 NK Receptor CL-6;p58.2 MHC Class-I-Specific NK Receptor;CD158b2;KIR2DL3;CD158B2;KIRCL23;NKAT2;KIR-K7b;KIR-K7c;KIR2DS5;KIRCL23;MGC129943;NKAT;NKAT2;NKAT2A;NKAT2B

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