Elabscience

PE Anti-Mouse CD150 Antibody[TC15-12F12.2]

Product Code:
 
E-AB-F1177UD
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rat
Antibody Isotype:
 
Rat IgG2a, λ
Antibody Clone:
 
TC15-12F12.2
Regulatory Status:
 
RUO
Target Species:
 
Mouse
Application:
 
Flow Cytometry
Shipping:
 
Ice packs
Storage:
 
Store at 2-8°C and protected from prolonged exposure to light. Do not freeze.
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C57BL/6 splenocytes cells are stained with PE Anti-Mouse CD150 Antibody (filled gray histogram) or PE Rat IgG2a, &lamda; Isotype Control (empty black histogram).
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C57BL/6 splenocytes cells are stained with PE Anti-Mouse CD150 Antibody (filled gray histogram) or PE Rat IgG2a, &lamda; Isotype Control (empty black histogram).

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CodeSizePrice
E-AB-F1177UD-25ug25ug£129.00
Quantity:
E-AB-F1177UD-100ug100ug£251.00
Quantity:
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This product comes from: China.
Typical lead time: 14-21 working days.
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Further Information

Abbreviation:
CD150/SLAM
Background:
CD150 is a 75-95 kD member of the immunoglobulin superfamily, also known as SLAM (signaling lymphocyte activation molecule) or IPO-3. CD150, a single chain type I transmembrane molecule, is expressed on thymocytes, T cell subsets, B cells, dendritic cells, and endothelial cells. The expression is upregulated upon activation. CD150 expression has been shown to be maintained on Th1 but not Th2 clones. T regulatory cells express a relatively high level of CD150. Antibodies against CD150 have been shown to augment IFN-γ production by Th1 cells, especially when co-stimulated through the TCR. CD150 associates with the src homology 2-domain-containing protein tyrosine phosphatase SHP-2, and this association is thought to be involved in signal transduction. In combination with CD48, CD150 is a useful marker for hematopoietic stem cell studies.
Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Concentration:
0.2 mg/mL
Conjugation:
PE
GeneID:
27218
Target Synonym:
Slam;Slamf1;CD 150;Signaling lymphocytic activation molecule;
UNIProt ID:
Q9QUM4
Usage:
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 ug/10^6 cells in 100 uL volume].

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