Elabscience

FITC Anti-Mouse CD279/PD-1 Antibody[29F.1A12]

Product Code:
 
E-AB-F1131UC
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rat
Antibody Isotype:
 
Rat IgG2a, κ
Antibody Clone:
 
29F.1A12
Regulatory Status:
 
RUO
Target Species:
 
Mouse
Application:
 
Flow Cytometry
Shipping:
 
Ice packs
Storage:
 
Store at 2-8°C and protected from prolonged exposure to light. Do not freeze.
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C57BL/6 murine splenocytes are stained with APC Anti-Mouse CD4 Antibody and FITC Anti-Mouse CD279/PD-1 Antibody (Left). Splenocytes are stained with APC Anti-Mouse CD4 Antibody and FITC Rat IgG2a, κ Isotype Control (Right).
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C57BL/6 murine splenocytes are stained with APC Anti-Mouse CD4 Antibody and FITC Anti-Mouse CD279/PD-1 Antibody (Left). Splenocytes are stained with APC Anti-Mouse CD4 Antibody and FITC Rat IgG2a, κ Isotype Control (Right).

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CodeSizePrice
E-AB-F1131UC-25ug25ug£113.00
Quantity:
E-AB-F1131UC-100ug100ug£189.00
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Further Information

Abbreviation:
CD279/PD-1
Background:
CD279, also known as programmed death-1 (PD-1), is a 50-55 kD glycoprotein belonging to the CD28 family of the Ig superfamily. PD-1 is expressed on activated splenic T and B cells and thymocytes. It is induced on activated myeloid cells as well. PD-1 is involved in lymphocyte clonal selection and peripheral tolerance through binding its ligands, B7-H1 (PD-L1) and B7-DC (PD-L2). It has been reported that PD-1 and PD-L1 interactions are critical to positive selection and play a role in shaping the T cell repertoire. PD-L1 negative costimulation is essential for prolonged survival of intratesticular islet allografts.
Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Concentration:
0.5 mg/mL
Conjugation:
FITC
GeneID:
18566
Target Synonym:
PD-1; Programmed Death-1;
UNIProt ID:
Q02242
Usage:
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 ug/10^6 cells in 100 uL volume].

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