Elabscience

APC Anti-Mouse CD103 Antibody[M290]

Product Code:
 
E-AB-F1090E
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rat
Antibody Isotype:
 
Rat IgG2a, κ
Antibody Clone:
 
M290
Regulatory Status:
 
RUO
Target Species:
 
Mouse
Application:
 
Flow Cytometry
Shipping:
 
Ice packs
Storage:
 
Store at 2-8°C and protected from prolonged exposure to light. Do not freeze.
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C57BL/6 murine splenocytes are stained with FITC Anti-Mouse CD3 Antibody and APC Anti-Mouse CD103 Antibody (Left). Splenocytes are stained with FITC Anti-Mouse CD3 Antibody and APC Rat IgG2a, κ Isotype Control (Right).
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C57BL/6 murine splenocytes are stained with FITC Anti-Mouse CD3 Antibody and APC Anti-Mouse CD103 Antibody (Left). Splenocytes are stained with FITC Anti-Mouse CD3 Antibody and APC Rat IgG2a, κ Isotype Control (Right).

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CodeSizePrice
E-AB-F1090E-50Tests50Tests£159.00
Quantity:
E-AB-F1090E-100Tests100Tests£202.00
Quantity:
E-AB-F1090E-100Testsx2100Testsx2£297.00
Quantity:
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Further Information

Abbreviation:
CD103
Background:
CD103 is a type I transmembrane glycoprotein known as αE integrin or Integrin αIEL chain. It belongs to the integrin family and is primarily found on intestinal intraepithelial lymphocytes (IEL). CD103 is also expressed on a subpopulation of lamina propria T cells, epithelial dendritic cells, lamina propria-derived dendritic cells, and a small subset of peripheral lymphocytes. T regulatory cells express high level of CD103. The CD103 expression on lymphocytes can be induced upon activation and TGF-β stimulation. In association with integrin β7, CD103 is expressed as αE/β7 heterodimer. Mature CD103 protein can be cleaved into 2 chains, a 150 kD (C-terminal) chain and a 25 kD (N-terminal) chain, which remain linked by disulfide bonds. CD103 binds to E-cadherin and mediates homing of lymphocytes to the intestinal epithelium.
Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Concentration:
5 uL/Test
Conjugation:
APC
GeneID:
16407
Target Synonym:
Integrin alpha-E;Itgae;Integrin alpha M290;CD103;
UNIProt ID:
Q60677
Usage:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 uL of antibody per test (million cells in 100 uL staining volume or per 100 uL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

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