Elabscience

p16 Polyclonal Antibody

Product Code:
 
E-AB-40264
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Rat
Applications:
  • Immunofluorescence (IF)
  • Immunohistochemistry (IHC)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze / thaw cycles.
1 / 2
Immunohistochemistry of paraffinembedded Human ovarian using p16 Polyclonal Antibody at dilution of 1:100
2 / 2
Immunofluorescence analysis of PC-3 cells using p16 Polyclonal Antibody at dilution of 1:100
❮❯

Immunohistochemistry of paraffinembedded Human ovarian using p16 Polyclonal Antibody at dilution of 1:100
Immunofluorescence analysis of PC-3 cells using p16 Polyclonal Antibody at dilution of 1:100

No additional charges, what you see is what you pay! *

CodeSizePrice
E-AB-40264-20uL20uL£120.00
Quantity:
E-AB-40264-60uL60uL£160.00
Quantity:
E-AB-40264-120uL120uL£230.00
Quantity:
E-AB-40264-200uL200uL£331.00
Quantity:
Prices exclude any Taxes / VAT
How to order with us   Contact us
Stay in control of your spending. These prices have no additional charges, not even shipping!
* Rare exceptions are clearly labelled (only 0.14% of items!).
Multibuy discounts available! Contact us to find what you can save.
This product comes from: China.
Typical lead time: 14-21 working days.
Contact us for more accurate information.
  • Further Information
  • Documents
  • Show All

Further Information

Abbreviation:
p16
Background:
This gene generates several transcript variants which differ in their first exons. At least three alternatively spliced variants encoding distinct proteins have been reported, two of which encode structurally related isoforms known to function as inhibitors of CDK4 kinase. The remaining transcript includes an alternate first exon located 20 Kb upstream of the remainder of the gene; this transcript contains an alternate open reading frame (ARF) that specifies a protein which is structurally unrelated to the products of the other variants. This ARF product functions as a stabilizer of the tumor suppressor protein p53 as it can interact with, and sequester, the E3 ubiquitin-protein ligase MDM2, a protein responsible for the degradation of p53.
Buffer:
PBS with 0.05% Proclin300 and 50% glycerol, pH7.4.
Concentration:
0.82 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:200 IF 1:100-1:200
Immunogen:
Recombinant Rat Cyclin-dependent kinase inhibitor 2A protein
Purification method:
Antigen Affinity Purification
Target Synonym:
CCM2;CDK4 inhibitor p16 INK4;CDK4I;CDKN2;CDKN2A;Cell cycle negative regulator beta;CMM2;Cyclin dependent kinase 4 inhibitor A;Cyclin dependent kinase inhibitor 2A (melanoma p16 inhibits CDK4);Cyclin Dependent Kinase Inhibitor 2A
UNIProt ID:
Q9R0Z3

Documents