Elabscience

FZD6 Polyclonal Antibody

Product Code:
 
E-AB-63423
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Mouse
  • Rat
Application:
 
Western Blot (WB)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze / thaw cycles.
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Western blot analysis of extracts of various cell line using FZD6 Polyclonal Antibody at dilution of 1:1000.

Western blot analysis of extracts of various cell line using FZD6 Polyclonal Antibody at dilution of 1:1000.

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CodeSizePrice
E-AB-63423-60uL60uL£210.00
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E-AB-63423-120uL120uL£291.00
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E-AB-63423-200uL200uL£431.00
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This product comes from: China.
Typical lead time: 14-21 working days.
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Further Information

Abbreviation:
FZD6
Background:
This gene represents a member of the 'frizzled' gene family, which encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The protein encoded by this family member contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, and seven transmembrane domains, but unlike other family members, this protein does not contain a C-terminal PDZ domain-binding motif. This protein functions as a negative regulator of the canonical Wnt/beta-catenin signaling cascade, thereby inhibiting the processes that trigger oncogenic transformation, cell proliferation, and inhibition of apoptosis. Alternative splicing results in multiple transcript variants, some of which do not encode a protein with a predicted signal peptide.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Calculated MW:
75kDa/79kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:1000-1:2000
Immunogen:
Recombinant fusion protein of human FZD6 (NP_003497.2).
ObservedMW:
79kDa
Purification method:
Affinity purification
Target Synonym:
FZD6;FZ-6;FZ6;HFZ6;NDNC10
UNIProt ID:
O60353

Documents