Elabscience

DNAJB14 Polyclonal Antibody

Product Code:
 
E-AB-63811
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Application:
 
Western Blot (WB)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze / thaw cycles.
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Western blot analysis of extracts of various cell lines using DNAJB14 Polyclonal Antibody at 1:1000 dilution.
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Western blot analysis of extracts of various cell lines using DNAJB14 Polyclonal Antibody at 1:1000 dilution.

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E-AB-63811-60uL60uL£210.00
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E-AB-63811-120uL120uL£291.00
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E-AB-63811-200uL200uL£431.00
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This product comes from: China.
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Further Information

Abbreviation:
DNAJB14
Background:
Acts as a co-chaperone with HSPA8/Hsc70; required to promote protein folding and trafficking, prevent aggregation of client proteins, and promote unfolded proteins to endoplasmic reticulum-associated degradation (ERAD pathway. Acts by determining HSPA8/Hsc70's ATPase and polypeptide-binding activities. Can also act independently of HSPA8/Hsc70: together with DNAJB12, acts as a chaperone that promotes maturation of potassium channels KCND2 and KCNH2 by stabilizing nascent channel subunits and assembling them into tetramers. While stabilization of nascent channel proteins is dependent on HSPA8/Hsc70, the process of oligomerization of channel subunits is independent of HSPA8/Hsc70. When overexpressed, forms membranous structures together with DNAJB12 and HSPA8/Hsc70 within the nucleus; the role of these structures, named DJANGOs, is still unclear.
Buffer:
PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Calculated MW:
33kDa/42kDa
Concentration:
1 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:1000-1:4000
Immunogen:
Recombinant fusion protein of human DNAJB14
ObservedMW:
42kDa
Purification method:
Affinity purification
Target Synonym:
DNAJB14;EGNR9427;PRO34683
UNIProt ID:
Q8TBM8

Documents